The RESPImmun Faculty

	Herbert STROBL, MD Role of TGF-β ligand signaling in dendritic cells (DC)-dependent immuno-regulation in lung cancer
Otto Loewi Research Centre, Division of Immunology and Pathophysiology, Medical University of Graz, Heinrichstraße 31a, A-8010 Graz; phone: +43-676-7576195, fax: +43-316-385 79609, ✉ e-mail
websites: [RESPImmun]
• Profile     • Curriculum vitae     • PhD students     • Grants     • Publications ⏬

List of publications:

• See ⏩ Fodok Med Uni Graz

10 most significant publications:

1. Lim CX, Lee B, Geiger O, Passegger C, Beitzinger M, Romberger J, Stracke A, Högenauer C, Stift A, Stoiber H, Poidinger M, Zebisch A, Meister G, Williams A, Flavell RA, Henao-Mejia J, Strobl H: miR-181a Modulation of ERK-MAPK Signaling Sustains DC-SIGN Expression and Limits Activation of Monocyte-Derived Dendritic Cells. Cell Rep, 2020; 30(11):​3793–3805.e5.
2. Borek I, Köffel R, Feichtinger J, Spies M, Glitzner-Zeis E, Hochgerner M, Sconocchia T, Krump C, Tam-Amersdorfer C, Passegger C, Benezeder T, Tittes J, Redl A, Painsi C, Thallinger GG, Wolf P, Stary G, Sibilia M, Strobl H: BMP7 aberrantly induced in the psoriatic epidermis instructs inflammation-associated Langerhans cells. J Allergy Clin Immunol, 2020; 145(4):​1194–1207.e11.
3. Jurkin J, Krump C, Köffel R, Fieber C, Schuster C, Brunner PM, Borek I, Eisenwort G, Lim C, Mages J, Lang R, Bauer W, Mechtcheriakova D, Meshcheryakova A, Elbe-Bürger A, Stingl G, Strobl H: Human skin dendritic cell fate is differentially regulated by the monocyte identity factor Kruppel-like factor 4 during steady state and inflammation. J Allergy Clin Immunol, 2017; 139(6):​1873–1884.e10.
4. Köffel R, Meshcheryakova A, Warszawska J, Hennig A, Wagner K, Jörgl A, Gubi D, Moser D, Hladik A, Hoffmann U, Fischer MB, van den Berg W, Koenders M, Scheinecker C, Gesslbauer B, Knapp S, Strobl H: Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation. Blood, 2014; 124(17):​2713–2724.
5. Yasmin N, Bauer T, Modak M, Wagner K, Schuster C, Köffel R, Seyerl M, Stöckl J, Elbe-Bürger A, Graf D, Strobl H: Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation. J Exp Med, 2013; 210(12):​2597–2610.
6. Bauer T, Zagórska A, Jurkin J, Yasmin N, Köffel R, Richter S, Gesslbauer B, Lemke G, Strobl H: Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis. J Exp Med, 2012; 209(11):​2033–2047.
7. Göbel F, Taschner S, Jurkin J, Konradi S, Vaculik C, Richter S, Kneidinger D, Mühlbacher C, Bieglmayer C, Elbe-Bürger A, Strobl H: Reciprocal role of GATA-1 and vitamin D receptor in human myeloid dendritic cell differentiation. Blood, 2009; 114(18):​3813–3821.
8. Jörgl A, Platzer B, Taschner S, Heinz LX, Höcher B, Reisner PM, Göbel F, Strobl H: Human Langerhans-cell activation triggered in vitro by conditionally expressed MKK6 is counterregulated by the downstream effector RelB. Blood, 2007; 109(1):​185–193.
9. Taschner S, Koesters C, Platzer B, Jörgl A, Ellmeier W, Benesch T, Strobl H: Down-regulation of RXRα expression is essential for neutrophil development from granulocyte / monocyte progenitors. Blood, 2007; 109(3):​971–979.
10. Heinz LX, Platzer B, Reisner PM, Jörgl A, Taschner S, Göbel F, Strobl H: Differential involvement of PU.1 and Id2 downstream of TGF-β1 during Langerhans-cell commitment. Blood, 2006; 107(4):​1445–1453.

31.07.2020 RESPImmun · Doctoral Programme “Immune Modulation in Respiratory Diseases”